These benefits offer DEPOXETINE as the most effective, the safest & most convenient treatment of Premature Eiaculation.
DEPOXETINE
Is
on-demand treatment for premature eiaculation 6
Enhances
normal eiaculation time upto 4times 7
Is
rapidly absorbed & rapidly eliminated6
Is
unaffected by multiple drug using 7
Has
no cardiovascular adverse effect 8
Say
YES to c and NO to other drugs for PE
Prescribing
information
Composition:Depoxetine : Tablet: Each
film coated tablet contains Daoixetine Hydrochloride INN equivalent to
Dapoxetine 30mg.
Pharmacological
Information:Dapoxetine Hydrochloride is a white powder substance
and water-soluble. Dapoxetine Hydrochloride works by inhibiting the serotonin transporter,
increasing serotonin”s action at the post cyanotic cleft and as a consequence prompting
ejaculatory delay .Dapoxetine Hydrochloride is absorbed and eliminated rapidly
from the body .Its fast acting property makes it for the treatment of premature
ejaculation. Dapoxetine Hydrochloride is distributed rapidly in the body.
Greater that 99% of Dapoxetine Hydrochloride is bound to the plasma protein.
The mean steady state volume is 162L. Its initial half-life is
1.31hours.Dapoxetine Hydrochloride is metabolized extensively in the liver and
kidney by multiple enzymes such as CyP2D6,CyP3A4, and flavin monooxygenase 1
(FMO1)
Clinical
Information:Indications and
Usage: DEPOXETINE is indicated
for the treatment of- Premature ejaculation, Poor control over ejaculation
Dosage and Administration: The recommended starting dose for all patients is
30mg, taken as needed approximately 30-60 minutes prior to sexual activity.
Dose may be increased to the maximum recommended of 60 mg . Contracations:Dapoxetine
Hydrochlride is contraindicated to whom who has hyper sensitivity to it or any
component of this product. Precautions: Dapoxetine Hydrochloride is only
indicated in men with premature ejaculation. Drug Interaction: Potential
serious reactions with MAOIs. Inhibits metabolism of thioridazine. Risk of
serotonergic-assocated effects with serotonergic medicinal/herbal
products(including L-tryptophans, tramadol, linezolid,SSRIs, SNRIs, Lithium
& St. john”s wort prep). CNS –active medicinal products. Possible reduction
of clearance with CYPD6, CYP3A4 & flavin monooxygenase 1 inhibitors.
Side
Effects: Side effects are law
compared with many drugs. Such as dizziness, nausea, dry mouth, flatulence etc.
Pharmaceutical Information:Storge
Condition: Store in a cool and dry place, away from light. Keep out of the
reach of children.
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